Pirooz  Eghtesady, MD, PhD

Pirooz Eghtesady, MD, PhD

  • Emerson Chair in Pediatric Cardiothoracic Surgery at St. Louis Children’s Hospital
  • Chief, Section of Pediatric Cardiothoracic Surgery
  • Cardiothoracic Surgeon-in-Chief,  St. Louis Children's Hospital

Medical School

MD, UCLA School of Medicine, Los Angeles, CA, 1993

Graduate School

PhD, Molecular Biology and Immunology, UCLA, Los Angeles, CA 1993

Post Doctoral Education

Resident in General Surgery, Stanford University Hospital, 1998

Professor Alain Carpentier Service-Fellow in Cardiovascular Surgery, Broussais Hospital, Paris, France, 1999

Professor Claude Planché Service-Fellow in Pediatric Cardiac Surgery, Marie Lannelongue Hospital, Paris, France, 1999

Resident in Cardiothoracic Surgery, Johns Hopkins Hospital, 1998-2001

Fellow in Pediatric Cardiac Surgery, U.C.S.F./Stanford University Hospital, 2001-2002

Board Certifications

General Surgery--Certified
Thoracic Surgery--Certified
Congenital Heart Surgery--Certified

Honors and Awards

2017, Named to Best Doctors in America

2015 Pediatric Hospital Medicine Research Excellence Award (inaugural award) for role as co-author on a publication most likely to influence practice or policy: "Rates and impact of potentially preventable readmissions at children's hospitals"

International Conference of Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, 2005, Hershey, PA
- John Waldhausen, MD- Young Investigator Award

American Academy of Pediatrics, 2003, New Orleans, LA
- Cardiology and Cardiac Surgery Section
- 1st Place, Basic Sciences – Young Investigator Award

Perinatal Research Society, 2003, Charleston SC
- NIH Young Investigator Travel Award

Johns Hopkins Hospital
- Vincent L. Gott Award, 2000

Stanford University Hospital
- John Henry Smith Award, 1997

Clinical Interests

Pediatric Cardiology
Cardiac Surgery
Congenital Heart Disease in Children

Research Interests

2009-2014 Principal Investigator, National Institutes of Health, Heart, Lung, and Blood, 1R01HL098634-01, Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus?

2011-2013 Principal Investigator, National Institutes of Health, Heart, Lung, and Blood 1 R21 HL104391-01A1 Developing an animal model of HLHS: role of immune mediated injury

2011-2012 Principal Investigator, Saving Tiny Hearts Society, Mechanisms in the pathogenesis of HLHS
Dr. Eghtesady's laboratory research focuses on the pathogenesis of congenital heart diseases, with particular emphasis on aortic stenosis and hypoplastic left heart syndrome. See Eghtesady Lab website.
US2007/0105168 "Diagnosis and Prevention of Fetal Heart Disease," filed 10/4/06

US2007/0260218 "Cannula with Removable Sleeve," filed 5/5/06

WO2009/032168 "Non-Invasive Fetal Blood Oxygen Monitoring System and Associated Method," filed 8/28/08

Selected Publications

Miller JR, Simpson KE, Epstein DJ, Lancaster TS, Henn MC, Schuessler RB, Balzer DT, Shahanavaz S, Murphy JJ, Canter CE, Eghtesady P, Boston US. Improved survival after heart transplant for failed Fontan patients with preserved ventricular function. J. Heart Lung Transpl 2016 Mar 10. PMID: 27068035

Blume ED, Rosenthal DN, Rossano JW, Baldwin JT, Eghtesady P, Morales DL, Cantor RS, Conway J, Lorts A, Almond CS, Naftel DC, Kirklin JK; PediMACS Investigators. Outcomes of children implanted with ventricular assist devices in the United States: First analysis of the Pediatric Interagency Registry for Mechanical Circulatory Support (PedMACS). J Heart Lung Transplant. 2016 May;35(5):578-84. PMID: 27009673

Gazit AZ, Sweet SC, Grady RM, Boston US, Huddleston CB, Hoganson DM, Shepard M, Raithel S, Mehegan M, Doctor A, Spinella PC, Eghtesady P. Recommendations for utilization of the paracorporeal lung assist device in neonates and young children with pulmonary hypertension. Pediatr Transplant. 2016 Mar;20(2):256-70. PMID: 26899454

Saini, A, Hartman M, Gage BF, Eghesady P, Gazit A, Said A, Boston U, Spinella P. Incidence of Platelet Dysfunction by Thromboelastography-Platelet Mapping in Children Supported with ECMO: A Pilot Retrospective Study. Frontiers in Pediatrics 2016 Jan 6;3:116. PMID: 26779465

Kirklin JK, Huddleston CB, Eghtesady P, Bacha EA. Health-Related Quality of Life in Adult Survivors after the Fontan Operation.Semin Thorac Cardiovasc Surg 2015 Autumn;27(3):307-8. PMID: 26708373

Martinez SC, Eghtesady P, Bhalla S, Ludbrook PA. Scimitar Syndrome: Multimodal Imaging Before and After Repair. Tex Heart Inst J. 2015 Dec 1;42(6):593-5. PMID: 26664322

Grady RM, Eghtesady P. Potts Shunt and Pediatric Pulmonary Hypertension: What We Have Learned. Ann Thorac Surg. 2016 Apr:101(4):1539-43. PMID: 26518375

Martinez SC, Byku M, Novak EL, Cedars AM, Eghtesady P, Ludbrook PA, Billadello JJ. Increased Body Mass Index Is Associated with Congestive Heart Failure and Mortality in Adult Fontan Patients.Congenit. Heart Dis. 2016 Jan;11(1):71-9. PMID: 26365670

Eghtesady P. 50th Anniversary landmark commentary on Bove EL, Behrendt DM. Open-heart surgery in the first week of life. Ann Thorac Surg. 2015 Aug;100(2):387-8. PMID: 26234827

Miller JR, Epstein DT, Henn MC, Guthrie T, Schuessler RB, Simpson KE, Canter CE, Eghtesady P, Boston US. Early biventricular assist device use in children: a single center review of 31 patients. ASAIO J. 2015 Nov-Dec;61(6):688-94. PMID: 26186261

Cole CR, Eghtesady P. The myocardial and coronary histopathology and pathogenesis of hypoplastic left heart syndrome. Cardiol Young 2016 Jan;26(1):19-29. PMID: 26152503

Eghtesady. P. Primary pulmonary vein stenosis: can we expect different results? J. Thorac Cardiovasc Surg 2015 Jul;150(1):188-9. PMID: 26126465

Sparks J, Epstein D, Baltagi S, Mehegan ME, Simpson KE, Canter CE, Silvestry S, Eghtesady P, Boston US. Continous flow device support in children using the HeartWare HVAD: 1000 days of lessons learned from a single center experience. ASAIO J. 2015 Sep-Oct;61(5):569-73. PMID: 25967955

Miller JR, Boston US, Epstein DJ, Henn MC, Lawrance CP, Kallenbach J, Simpson KE, Canter CE, Eghtesady P. Pediatric Quality of Life while supported by a Ventricular Assist Device. Congenit Heart Dis. 2015 Jul-Aug;10(4):E189-96. PMID: 25864509

Miller JR, Lancaster TS, Eghtesady P. Current approaches to device implantation in pediatric and congenital heart disease patients. Expert Rev Cardiovasc Ther. 2015 Apr;13(4):417-27. PMID: 25732410 

Pub Med page for Pirooz Eghtesady, MD, PhD


Eghtesady P. Hyoplastic Left Heart Syndrome. In Encyclopedia of Molecular Mechanisms of Diseases, © 2008, Springer-Verlag Publishing, Heidelberg, Germany.

Eghtesady P, Stevens J. The Intern Survival Guide to the Stanford Cardiac Surgery Service. © 1994.

Eghtesady P, Kronenberg M. The Function of ãä T-lymphocytes and Te Non-classical Class I Molecules. © 1992, University of California Publishing, Los Angeles, CA.

Hershberg R, Eghtesady P, Kronenberg M. Intestinal Lymphocytes and Epithelium Express the Thymus Leukemia Antigen in “The Immunology of the Gut” from the Proceedings of International Congress on Mucosal Immunology V, Tokyo. © 1990. Excerpta Medical International Congress Series, Elsevier Science Publishing BV.