Pirooz  Eghtesady, MD, PhD

Pirooz Eghtesady, MD, PhD

  • Chief, Section of Pediatric Cardiothoracic Surgery
  • Cardiothoracic Surgeon-in-Chief,  St. Louis Children's Hospital

Medical School

MD, UCLA School of Medicine, Los Angeles, CA, 1993

Graduate School

PhD, Molecular Biology and Immunology, UCLA, Los Angeles, CA 1993

Post Doctoral Education

Resident in General Surgery, Stanford University Hospital, 1998

Professor Alain Carpentier Service-Fellow in Cardiovascular Surgery, Broussais Hospital, Paris, France, 1999

Professor Claude Planché Service-Fellow in Pediatric Cardiac Surgery, Marie Lannelongue Hospital, Paris, France, 1999

Resident in Cardiothoracic Surgery, Johns Hopkins Hospital, 1998-2001

Fellow in Pediatric Cardiac Surgery, U.C.S.F./Stanford University Hospital, 2001-2002

Board Certifications

General Surgery--Certified
Thoracic Surgery--Certified
Congenital Heart Surgery--Certified

Honors and Awards

International Conference of Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion, 2005, Hershey, PA
- John Waldhausen, MD- Young Investigator Award

American Academy of Pediatrics, 2003, New Orleans, LA
- Cardiology and Cardiac Surgery Section
- 1st Place, Basic Sciences – Young Investigator Award

Perinatal Research Society, 2003, Charleston SC
- NIH Young Investigator Travel Award

Johns Hopkins Hospital
- Vincent L. Gott Award, 2000

Stanford University Hospital
- John Henry Smith Award, 1997

Clinical Interests

Pediatric Cardiology
Cardiac Surgery
Congenital Heart Disease in Children

Research Interests

2009-2014 Principal Investigator, National Institutes of Health, Heart, Lung, and Blood, 1R01HL098634-01, Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus?

2011-2013 Principal Investigator, National Institutes of Health, Heart, Lung, and Blood 1 R21 HL104391-01A1 Developing an animal model of HLHS: role of immune mediated injury

2011-2012 Principal Investigator, Saving Tiny Hearts Society, Mechanisms in the pathogenesis of HLHS
Dr. Eghtesady's laboratory research focuses on the pathogenesis of congenital heart diseases, with particular emphasis on aortic stenosis and hypoplastic left heart syndrome. See Eghtesady Lab website.
US2007/0105168 "Diagnosis and Prevention of Fetal Heart Disease," filed 10/4/06

US2007/0260218 "Cannula with Removable Sleeve," filed 5/5/06

WO2009/032168 "Non-Invasive Fetal Blood Oxygen Monitoring System and Associated Method," filed 8/28/08

Selected Publications

Petrucci O, O'Brien SM, Jacobs ML, Jacobs JP, Manning PB, Eghtesady P. Risk factors for mortality and morbidity after the Neonatal Blalock-Taussig Shunt Procedure. 2011 Aug;92(2):642-52.

Raake J, Johnson B, Seger B, Manning PB, Eghtesady P, Boesch P, Rutter M, Woodard A, Chima RS. Extracorporeal membrane oxygenation, extubation, and lung-recruitment maneuvers as rescue therapy in a patient with tracheal dehiscence following slide tracheoplasty. Respir Care. 2011 Aug;56(8):1198-202.

Lam CT, Baker RS, Clark KE, Eghtesady P. Changes in fetal ovine metabolism and oxygen delivery with fetal bypass. Am J Physiol Regul Integr Comp Physiol. 2011;301:R105-R115.

Anderson JB, Kalkwarf HJ, Kehl JE, Eghtesady P, Marino BS. Lower weight-for-age Z-score and infection risk after the Fontan procedure. 2011 May;91(5):1460-6.

Duffy JY, Petrucci O, Baker RS, Lam CT, Reed CA, Everman DJ, Eghtesady P. Myocardial function after fetal cardiac bypass in an ovine model. J Thorac Cardiovasc Surg. 2011 Apr; 141(4):961-968.e.1

Eghtesady P, Brar A, Hall M. Seasonality of Hypoplastic Left Heart Syndrome in the United States: a 10-Year time-series analysis. J Thorac Cardiovasc Surg. 2011 Feb;141(2):432-8.

Eghtesady P, Michelfelder E, Knilans TK, Livingston J, Manning PB, Crombleholme T. Fetal surgical management of congenital heart block in a hydropic fetus: lessons learned from a clinical experience. J Thorac Cardiovasc Surg. 2011 Mar;141(3)835-7.

Petrucci O, Baker RS, Lam CT, Reed CA, Duffy JY, Eghtesady P. Fetal right ventricular myocardial function is better preserved by fibrillatory arrest during fetal cardiac bypass. Ann Thorac Surg. 2010 Oct;90(4):1324-31.

Anderson JB, Beekman RH, Eghtesady P, Kalkwarf HJ, Uzark K, Kehl JE, Marino BS. Predictors of poor weight gain in infants with a single ventricle. J Pediatr. 2010 Sep:157(3)407-13, 413.e.1.

Reed CA, Baker RS, Lam CT, Hilshorst JL, Ferguson R, Lombardi J, Eghtesady P. Application of near-infrared spectroscopy during fetal cardiac surgery. J Surg Res. 2009 November 29 [Epub ahead of print]

Petrucci O, Khoury PR, Manning, PB, Eghtesady P. Outcomes of bidirectional Glenn procedure in patients less than 3 months of age. J Thorac Cardiovasc Surg. 2010 Mar:139(3):562-8.

Anderson JB, Beekman RH, Border WL, Kalkwarf HJ, Khoury PR, Uzark K, Eghtesady P, Marino BS. Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle. J Thorac Cardiovasc Surg. 2009 Aug;138(2):397-404.e1.

Baker RS, Lam CT, Heeb E, Eghtesady P. Dynamic fluid shifts induced by fetal bypass. J Thorac Cardiovasc Surg. 2009 Mar;137(3):714-22.

Heeb EA, Baker RS, Lam C, Basu M, Lubbers W, Duffy JY, Eghtesady P. Role of natriuretic peptides in cGMP production in fetal cardiac bypass. Ann Thorac Surg. 2009 Mar;87(3):841-7.

Lam CT, Sharma S, Baker RS, Lombardi J, Clark KE, Eghtesady P. Fetal stress response to fetal cardiac surgery. Ann Thorac Surg. 2008 May;85(5):1719-27.

Pub Med page for Pirooz Eghtesady, MD, PhD

Chapters

Eghtesady P. Hyoplastic Left Heart Syndrome. In Encyclopedia of Molecular Mechanisms of Diseases, © 2008, Springer-Verlag Publishing, Heidelberg, Germany.

Eghtesady P, Stevens J. The Intern Survival Guide to the Stanford Cardiac Surgery Service. © 1994.

Eghtesady P, Kronenberg M. The Function of ãä T-lymphocytes and Te Non-classical Class I Molecules. © 1992, University of California Publishing, Los Angeles, CA.

Hershberg R, Eghtesady P, Kronenberg M. Intestinal Lymphocytes and Epithelium Express the Thymus Leukemia Antigen in “The Immunology of the Gut” from the Proceedings of International Congress on Mucosal Immunology V, Tokyo. © 1990. Excerpta Medical International Congress Series, Elsevier Science Publishing BV.